Description
Product Characteristics:
Aliases: CDEP antibody, Chondrocyte derived ezrin like protein antibody, Chondrocyte-derived ezrin-like protein antibody, FARP1 antibody, FARP1_HUMAN antibody, FERM RhoGEF and pleckstrin domain containing protein 1 antibody, FERM antibody, FERM RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) antibody, FERM, ARHGEF, and pleckstrin domain protein 1 antibody, PH domain-containing family C member 2 antibody, Pleckstrin homology domain-containing family C member 2 antibody, PLEKHC2 antibody, PPP1R75 antibody, protein phosphatase 1, regulatory subunit 75 antibody, RhoGEF and pleckstrin domain-containing protein 1 antibody
Target Information: This gene was originally isolated through subtractive hybridization due to its increased expression in differentiated chondrocytes versus dedifferentiated chondrocytes. The resulting protein contains a predicted ezrin-like domain, a Dbl homology domain, and a pleckstrin homology domain. It is believed to be a member of the band 4.1 superfamily whose members link the cytoskeleton to the cell membrane. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]